An improved postconditioning algorithm: Gradually increased reperfusion provides improved cardioprotection in rats

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An improved postconditioning algorithm: gradually increased reperfusion provides improved cardioprotection in rats.

The aim of the present study was to investigate whether a gradually increasing reperfusion algorithm, in which the brief reperfusion was lengthened as the duration of each reperfusion/reocclusion cycle remained fixed, enhances cardioprotection. Rats were randomized into 5 groups: the sham, reperfusion injury (R/I), gradually decreased reperfusion (GDR; 30/10‑25/15‑15/25‑10/30 sec of reperfusion...

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ژورنال

عنوان ژورنال: Molecular Medicine Reports

سال: 2013

ISSN: 1791-2997,1791-3004

DOI: 10.3892/mmr.2013.1544